Publications

Kohrt S, Baheerathan A, Prokscha J, Zwosta A, Sticht H, Thoma-Kress AK. (2024) Identification of a nuclear localization signal (NLS) in human transcription elongation factor ELL2. Cell Biochem Funct., accepted. 

Simon F, Thoma-Kress AK (2024) Intercellular transport of viral proteins. Editors: Jacek Z. Kubiak, Malgorzata Kloc. Springer Nature. Results Probl Cell Differ. 73:435-474. doi: 10.1007/978-3-031-62036-2_18.

de Mendoza C, Taylor G, Gessain A, Thoma-Kress AK, Bangham C, Vesterbacka J, Accolla R, Bazarbachi A, van Weyenbergh J, Cook L, Casseb J, Ramos JC, Rosadas C, Macchi B, Cassar O, Soriano V. (2024) Virology, pathogenesis, epidemiology and clinical management of HTLV-1 infection. Proceedings of the 30th HTLV European research network (HERN 2023). NeuroImmune Pharmacol. Ther.  https://doi.org/10.1515/nipt-2023-0025

Zeyn Y, Hobernik D, Wilk U, Pöhmerer J, Hieber C, Medina-Montano C, Röhrig N, Strähle CF, Thoma-Kress AK, Wagner E, Bros M*, Berger S* (2023) Transcriptional Targeting of Dendritic Cells Using an Optimized Human Fascin1 Gene Promoter. Int. J. Mol. Sci. 24(23):16938. *corresponding authors. doi.org/10.3390/ijms242316938

Kemeter L, Birzer A, Heym S, Thoma-Kress AK (2023) Milk transmission of mammalian retroviruses. Mircoorganisms. 11(7):1777. doi: 10.3390/microorganisms11071777. 

Rojo-Romanos T, Karpinski J, Millen S, Beschorner N, Simon F, Paszkowski-Rogacz M, Lansing F, Schneider PM, Sonntag J, Hauber J, Thoma-Kress AK, Buchholz F (2023) Precise excision of HTLV-1 provirus with a designer-recombinase. Mol. Therapy S1525-0016(23)00135-1. doi:10.1016/j.ymthe.2023.03.014. 

Schnell AP, Kohrt S, Aristodemou A, Taylor GP, Bangham CRM, Thoma-Kress AK (2022) HDAC inhibitors Panobinostat and Romidepsin enhance tax transcription in HTLV-1-infected cell lines and freshly isolated patients' T-cells. Front. Immunol. 13:978800. doi: 10.3389/fimmu.2022.978800                                                                                        

Heym S, Mohr CF, Engelbrecht HC, Fleckenstein B, Thoma-Kress AK (2022) Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses. Cancers. 14(3):537. doi: 10.3390/cancers14030537. 

Millen S, Thoma-Kress AK (2022)  Milk Transmission of HTLV-1 and the need for innovative prevention strategies. Front Med. 9:867147. doi: 10.3389/fmed.2022.867147.

Kohrt S, Strobel S, Mann MC, Sticht H, Fleckenstein B, Thoma-Kress AK (2021) Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation. Int. J. Mol. Sci. 2(24), 13597; doi: 10.3390/ijms222413597.

Schnell AP, Kohrt S, Thoma-Kress AK (2021) Latency Reversing Agents: Kick and Kill of HTLV-1? Int. J. Mol. Sci. 22(11):5545. doi: 10.3390/ijms22115545. 

Thoma-Kress AK, Desrosiers RC, Gack MU, Jung JU, Überla K, Kirchhoff F (2021) Biographical Feature: Bernhard Fleckenstein. J Virol. 95(17):e0089621. doi: 10.1128/JVI.00896-21.

Donhauser N, Socher E, Millen S, Heym S, Sticht H, Thoma-Kress AK (2020)  Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8. PLoS Pathogens, 16(9):e1008879. doi: 10.1371/journal.ppat.1008879.

Millen S, Meretuk L, Göttlicher T, Schmitt S, Fleckenstein B, Thoma-Kress AK (2020) A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells. Retrovirology. 17(1):30. doi: 10.1186/s12977-020-00538-w.

Thoma-Kress AK, Überla K (2020) Von der antiviralen Chemotherapie bis zur Immunintervention. Trillium Immunologie; 4(2).

Millen S, Gross C, Donhauser N, Mann MC, Péloponèse JM Jr, Thoma-Kress AK (2019) Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission. Front Microbiol. 10:2439. doi: 10.3389/fmicb.2019.02439.

Dohauser N, Heym S, Thoma-Kress AK (2018) Quantitating the Transfer of the HTLV-1 p8 Protein between T-cells by Flow Cytometry. Front Microbiol. 9:400. doi: 10.3389/fmicb.2018.00400.

Manicone M, Rende F, Cavallari I, Thoma-Kress AK, Ciminale V (2017) Expression of HTLV-1 Genes in T-cells using RNA Electroporation. In: Human T-Lymphotropic Viruses – Methods and Protocols. Editor: Claudio Casoli. Methods Mol Biol. 1582:155-170. DOI:10.1007/978-1-4939-6872-5_12.

Gross C, Thoma-Kress AK (2017) Reporter Systems To Study HTLV-1 Transmission. In: Human T-Lymphotropic Viruses – Methods and Protocols. Editor: Claudio Casoli. Methods Mol Biol. 1582:33-46.  DOI: 10.1007/978-1-4939-6872-5_3.

Gross C, Wiesmann V, Millen S, Kalmer M, Wittenberg T, Gettemans J, Thoma-Kress AK (2016) The Tax-inducible Actin-bundling Protein Fascin is Crucial for Release and Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1 (HTLV-1). PLoS Pathogens, 12(10):e1005916. DOI: 10.1371/journal.ppat.1005916 

Gross C, Thoma-Kress AK (2016) Molecular Mechanisms of HTLV-1 Cell-to-Cell Transmission. Viruses. 8(3),74. DOI: 10.3390/v8030074 

Wiesmann V, Groß C, Franz D, Thoma-Kreß AK, Wittenberg T. (2016) Combining Active Contours and Active Shapes for Segmentation of Fluorescently Stained Cells. Application to Virology. In: T. Tolxdorff et al. (Hrsg.). Informatik aktuell. Bildverarbeitung für die Medizin 2016. Springer-Verlag Berlin Heidelberg. Pp 122-127. DOI 10.1007/978-3-662-49465-3_23

Mohr CF, Gross C, Bros M, Reske-Kunz AB, Biesinger B, Thoma-Kress AK (2015) Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism. Virology. 485:481-491. doi: 10.1016/j.virol.2015.08.025. 

Thoma-Kress AK (2015) Humane T-Zell-Leukämieviren (HTLV-1, HTLV-2). In: Handbuch der Infektionskrankheiten-59. Erg. Lfg., Hrsg. Hofmann, F., Ecomed Verlag. 

Mohr CF, Kalmer M, Gross C, Mann MC, Sterz KR, Kieser A, Fleckenstein B, Kress AK (2014)
The tumor marker Fascin is induced by the EBV-encoded oncoprotein LMP1 via NF-kappaB signals in lymphocytes and contributes to their invasive migration. Cell Communication and Signaling. 12(1):46. doi: 10.1186/s12964-014-0046-x. 

Mann MC, Strobel S, Fleckenstein B, Kress AK (2014) The transcription elongation factor ELL2 is specifically upregulated in HTLV-1-infected T-cells and is dependent on the viral oncoprotein Tax. Virology. 464-465:98-110. doi: 10.1016/j.virol.2014.06.028. 

Kress AK, Fleckenstein B (2014) Adulte T-Zell-Leukämie durch das Humane T- lymphotrope Virus Typ 1 (HTLV-1). Onkologie heute, 05/2014, 12. Jahrgang, Juni 2014. 

Ooms M, Krikoni A, Kress AK, Simon V, Münk C (2012) APOBEC3A, APOBEC3B and APOBEC3H haplotype 2 restrict Human T-lymphotropic virus type I (HTLV-1). J Virol. 86:6097-108. doi: 10.1128/JVI.06570-11.  

Kress AK (2012) Humanes T-Zell-Leukämie Virus Typ 1 (HTLV-1) - Infektion, Pathogenese und Therapie. Retrovirus Bulletin; 4.

Kress AK*, Kalmer M, Rowan A, Grassmann R, Fleckenstein B (2011) The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-kappaB signals. Blood. 117:3609-3612. *corresponding author. doi: 10.1182/blood-2010-09-305805. 

Kress AK*, Grassmann R, Fleckenstein B (2011) Cell Surface Markers in HTLV-1 Pathogenesis. Viruses. 3, 1439-1459. *corresponding author. doi: 10.3390/v3081439.

Kress AK*, Schneider G, Pichler K, Kalmer M, Fleckenstein B, Grassmann R (2010) Elevated cyclic AMP (cAMP) levels in T lymphocytes transformed by human T cell lymphotropic virus type 1 (HTLV-1). J Virol. 84:8732-8742. *corresponding author. doi: 10.1128/JVI.00487-10.

Kress AK (2009) Neuigkeiten vom Humanen T-Zell-Leukämie Virus (HTLV): Eindrücke vom HTLV-Weltkongress. Retrovirus Bulletin; 4.

Pichler K, Kattan T, Gentzsch J, Kress AK, Taylor GP, Bangham CRM, Grassmann R (2008)  Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1-infected cultured and patients’ T cells by the viral Tax oncoprotein. Blood. 111(9):4741–51. doi: 10.1182/blood-2007-10-115220. 

Silbermann K, Pichler K, Kress AK (2008) Humanes T-Zell-Leukämie-Virus (HTLV-1): Pathomechanismen assoziierter Erkrankungen. Retrovirus Bulletin. 3: 7